Organometallic cages as vehicles for intracellular release of photosensitizers.
نویسندگان
چکیده
Water-soluble metalla-cages were used to deliver hydrophobic porphin molecules to cancer cells. After internalization, the photosensitizer was photoactivated, significantly increasing the cytotoxicity in cells. During the transport, the photosensitizer remains nonreactive to light, offering a new strategy to tackle overall photosensitization, a limitation often encountered in photodynamic therapy.
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ورودعنوان ژورنال:
- Journal of the American Chemical Society
دوره 134 2 شماره
صفحات -
تاریخ انتشار 2012